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Bringing GRAPPA to non-Cartesian MRI through SPARKLING: An application to MP-RAGE anatomical MRI

September 2025 Chaithya Giliyar Radhakrishna, Alexandre Vignaud, Maxime Bertrait, et al. ISMRM & ISMRT 2025-Annual Meeting & Exhibition · Conference abstract
#SPARKLING #Non-Cartesian Sampling #k-space Sampling #Parallel Imaging #Structural MRI #MRI

Abstract

Motivation: Well established clinically used parallel imaging techniques like GRAPPA and CAIPIRINHA are mostly limited to Cartesian sampling, and their extension to non-Cartesian sampling is not direct. Goal(s): We propose to extend the SPARKLING framework to ensure GRAPPA accelerated Cartesian sampling in k-space center, while allowing non-Cartesian sampling in the periphery. Approach: Through affine constraints, we can enforce Cartesian acceleration in the center of k-space, while allowing non-Cartesian sampling in the periphery. Results: Using 2x2 GRAPPA with SPARKLING trajectories for anatomical MRI with MPRAGE sequences enables 10x acceleration, achieving 1mm isotropic whole-brain scans in 1 minute. Impact: This novel technique will help bring conventional multi-coil acceleration to non-Cartesian imaging, which can be used independently to massively accelerate MR scans, enabling faster and higher resolution imaging, which will be beneficial for varied clinical applications.

Details

  • Type of work: Conference abstract
  • Venue: ISMRM & ISMRT 2025-Annual Meeting & Exhibition
  • Published: 16 September 2025
  • DOI: 10.58530/2025/4444
  • Authors: Chaithya Giliyar Radhakrishna, Alexandre Vignaud, Maxime Bertrait, Aurélien Massire, Michel Bottlaender, and Philippe Ciuciu
  • Data sources: ref.bib, OpenAlex

BibTeX

@inproceedings{radhakrishna2025bringing,
  title={Bringing GRAPPA to non-Cartesian MRI through SPARKLING: An application to MPRAGE anatomical MRI},
  author={Radhakrishna, Chaithya Giliyar and Vignaud, Alexandre and Bertrait, Maxime and Massire, Aur{\'e}lien and Bottlaender, Michel and Ciuciu, Philippe},
  booktitle={ISMRM \& ISMRT 2025-Annual Meeting \& Exhibition},
  year={2025}
}