Combining Cartesian and non-Cartesian acceleration techniques with SPARKLING for 1mm isotropic whole-brain MPRAGE in a minute
2026-05-29 Chaithya Giliyar Radhakrishna, Aurélien Massire, Blanche Bapst, et al. arXiv preprint arXiv:2605.31017

Purpose: T1-weighted MPRAGE remains a cornerstone of clinical anatomical imaging, yet its long acquisition times constrain routine use. Established acceleration techniques, namely Parallel Imaging (PI) and Compressed Sensing (CS), tend to introduce substantial noise and blurring when pushed to high acceleration…

On the Impact of Artifacts Induced by Mismatches Between Auto‐Calibration Signal and Accelerated 3D GRE Data at 11.7T
2025-10-18 Joseph Obriot, Franck Mauconduit, Vincent Gras, et al. Magnetic Resonance in Medicine

PURPOSE: field inhomogeneity artifacts arising from remote locations in the FOV and encountered in accelerated 3D gradient-recalled echo (GRE) sequences at ultra-high field, and at providing mitigation strategies. METHODS: Measurements were conducted at 11.7T using a head-shaped phantom and an accelerated 3D GRE…

Benchmarking 3D multi-coil NC-PDNet MRI reconstruction
2025-09-16 Asma Tanabene, Chaithya Giliyar Radhakrishna, Aurélien Massire, et al. 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI)

Motivation: Deep Neural Networks (DNNs) show promise in reconstructing undersampled MRI data but face challenges with non-Cartesian 3D multi-coil acquisitions due to high memory demands and training complexity. Goal(s): To address the research gap in validating DNNs performances for non-Cartesian data in 3D multi-coil…

Bringing GRAPPA to non-Cartesian MRI through SPARKLING: An application to MP-RAGE anatomical MRI
2025-09-16 Chaithya Giliyar Radhakrishna, Alexandre Vignaud, Maxime Bertrait, et al. ISMRM & ISMRT 2025-Annual Meeting & Exhibition

Motivation: Well established clinically used parallel imaging techniques like GRAPPA and CAIPIRINHA are mostly limited to Cartesian sampling, and their extension to non-Cartesian sampling is not direct. Goal(s): We propose to extend the SPARKLING framework to ensure GRAPPA accelerated Cartesian sampling in k-space…

gGRAPPA: A flexible, GPU-accelerated python package for fast and efficient generalized GRAPPA reconstruction
2025-09-16 Maxime Bertrait, Chaithya Giliyar Radhakrishna, Philippe Ciuciu ISMRM & ISMRT 2025-Annual Meeting & Exhibition

Motivation: Existing open-source MR reconstruction tools often fail to efficiently utilize GPU resources and lack support for generalized GRAPPA implementations. Many tools are limited to 2D or 3D reconstruction, and few incorporate advanced techniques such as 2D-CAIPIRINHA, which enhances imaging capabilities.

Non-cartesian 3D-SPARKLING vs cartesian 3D-EPI encoding schemes for functional magnetic resonance Imaging at 7 Tesla
2024-05-13 Zaineb Amor, Philippe Ciuciu, Chaithya Giliyar Radhakrishna, et al. Plos one

The quest for higher spatial and/or temporal resolution in functional MRI (fMRI) while preserving a sufficient temporal signal-to-noise ratio (tSNR) has generated a tremendous amount of methodological contributions in the last decade ranging from Cartesian vs. non-Cartesian readouts, 2D vs.